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Hypoxia-selective antitumor agents. I: Relationships between structure, redox properties and hypoxia-selective cytotoxicity for 4-substituted derivatives of nitracrineWILSON, W. R; ANDERSON, R. F; DENNY, W. A et al.Journal of medicinal chemistry (Print). 1989, Vol 32, Num 1, pp 23-30, issn 0022-2623, 8 p.Article

IMMUNOSUPPRESSIVE ACTIVITY OF LEDAKRINGIELDANOWSKI J; SKOWRONSKA J.1979; ARCH. IMMUNOL. THERAP. EXPER.; POL; DA. 1979; VOL. 27; NO 3; PP. 315-319; BIBL. 16 REF.Article

COMPLEXES OF NITRACRINE WITH DNA: STOICHIOMETRY OF BINDINGSZMIGIERO L; GNIAZDOWSKI M.1981; ARZNEIM.-FORSCH.; ISSN 0004-4172; DEU; DA. 1981; VOL. 31; NO 11; PP. 1875-1877; ABS. GER; BIBL. 10 REF.Article

EFFECT OF NITRACRINE (LEDAKRIN, C-283) AND ACTINOMYCIN D ON HETEROPOLYMER AND POLY A SYNTHESIS CATALYZED BY BACTERIAL RNA POLYMERASECIESIELSKA E; JAROS KAMINSKA B; SLASKA K et al.1979; STUD. BIOPHYS.; DDR; DA. 1979; VOL. 73; NO 2; PP. 141-146; ABS. RUS; BIBL. 6 REF.Article

EARLY EFFECT OF LEDAKRIN (A NITRO-DERIVATIVE OF ACRIDINE) ON CELL MEMBRANEPOPOWICZ P; PODSIALO H; KNAPOWSKI J et al.1980; ACTA PHYSIOL. POLON.; POL; DA. 1980; VOL. 31; NO 1; PP. 81-91; BIBL. 39 REF.Article

Mutagenic activity of nitracrine derivatives in Salmonella typhimurium: relationship to drug physicochemical parameters, and to bacterial uvrB and recA genes and plasmid pKM101FERGUSON, L. R; DENNY, W. A; O'ROURKE, S. M et al.Mutation research. 1989, Vol 223, Num 1, pp 13-22, issn 0027-5107Article

Are lethal effects of nitrarine on L5178Y cell sublines associated with DNA-protein crosslinks ?WALICKA, M; SZMIGIERO, L; CIESIELSKA, E et al.Biochemical pharmacology. 1993, Vol 46, Num 4, pp 615-620, issn 0006-2952Article

Mutagenic, recombinogenic and antimitochondrial effects of nitracrine analogues in Saccharomyces cerevisiaeFERGUSON, L. R; TURNER, P. M.Mutation research. 1987, Vol 187, Num 4, pp 209-217, issn 0027-5107Article

In vitro binding of nitracrine to DNA in chromatinWILMANSKA, D; SZMIGIERO, L; GNIAZDOWSKI, M et al.Zeitschrift für Naturforschung. C. A journal of biosciences. 1989, Vol 44, Num 3-4, pp 307-311, issn 0939-5075, 5 p.Article

Comparison of antitumor properties of nitracrine and amsacrine analogsMAZERSKA, Z; CHOŁODY, M; ŁUKOWICZ, J et al.Arzneimittel-Forschung. 1987, Vol 37, Num 11, pp 1276-1281, issn 0004-4172Article

Effect of intercalating and groove-binding ligands on formation of covalent complexes between nitracrine (Ledakrin, C-283) or 8-methoxypsoralen and DNAWILMANSKA, D; MAŁAGOCKA, E; SZMIGIERO, L et al.Biochimica et biophysica acta. 1984, Vol 782, Num 3, pp 285-294, issn 0006-3002Article

Design, synthesis and antiproliferative activity of novel aminosubstituted benzothiopyranoisoindolesCHRISTODOULOU, Antonios; KOSTAKIS, Ioannis K; KOURAFALOS, Vassilios et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 10, pp 3110-3112, issn 0960-894X, 3 p.Article

Acridine derivatives as chemotherapeutic agentsDENNY, William A.Current medicinal chemistry. 2002, Vol 9, Num 18, pp 1655-1665, issn 0929-8673Article

32P-post-labeling analysis of DNA adduct formation by antitumor drug nitracrine (ledakrin) and other nitroacridines in different biological systemsBARTOSZEK, A; KONOPA, J.Biochemical pharmacology. 1989, Vol 38, Num 8, pp 1301-1312, issn 0006-2952Article

Synthesis and antiproliferative activity of substituted benzopyranoisoindoles : A new class of cytotoxic compoundsHADJIPAVLOU, Christiana; KOSTAKIS, Ioannis K; POULI, Nicole et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 18, pp 4822-4825, issn 0960-894X, 4 p.Article

QSAR of acridines. II, Features of nitracrine analogs for high anti-tumor activity and selectivity on mice, searched by PCA and MRA methodsMAZERSKA, Z; MAZERSKI, J; LEDOCHOWSKI, A et al.Anti-cancer drug design. 1990, Vol 5, Num 2, pp 169-187, issn 0266-9536Article

Tautomerism and stereoisomerism of nitracrine, its nitro isomers and their protonated forms in solution examined by absorption and fluorescence spectroscopyRAK, J; BŁAZEJOWSKI, J; NOWACZYK, K et al.Journal of photochemistry and photobiology. A, Chemistry. 1991, Vol 61, Num 3, pp 343-363, issn 1010-6030Article

DNA damage and cytotoxicity of nitracrine in cultured HeLa cellsSZMIGIERO, L; STUDZIAN, K.Biochimica et biophysica acta. 1989, Vol 1008, Num 3, pp 339-345, issn 0006-3002Article

Mutagenicity of nitracrine analogues in Salmonella typhimurium: mutational specificity and activation by bacterial enzymes and rat-liver S9FERGUSON, L. R; TURNER, P. M; DENNY, W. A et al.Mutation research. 1987, Vol 187, Num 1, pp 1-9, issn 0027-5107Article

The intercalative DNA binding and antitumor activity of some bis-acridines related to nitracrineACHESON, R. M; TAYLOR, G. N; WARING, M. J et al.Chemico-biological interactions. 1985, Vol 53, Num 3, pp 371-375, issn 0009-2797Article

Frameshift mutagenesis by nitracrine analogues in wild-type, uvrB, polA and recA strains of Salmonella typhimurium, with and without plasmid pKM101FERGUSON, L. R; TURNER, P. M.Mutation research. 1987, Vol 184, Num 1, pp 13-21, issn 0027-5107Article

Reduction of the anticancer drug nitracrine. Access to dihydropyrazolo- and dihydropyrimidino-acridinesCHOLODY, W. M; LHOMME, M. F; LHOMME, J et al.Tetrahedron letters. 1987, Vol 28, Num 42, pp 5029-5032, issn 0040-4039Article

Pulse radiolysis studies of electron migration in DNA from DNA base-radical anions to nitroacridine intercalators in aqueous solutionANDERSON, R. F; PATEL, K. B; WILSON, W. R et al.Journal of the Chemical Society. Faraday transactions. 1991, Vol 87, Num 23, pp 3739-3746Article

Mutagenic and clastogenic activity of nitracrine analogues in cultured V79 Chinese hamster cellsFERGUSON, L. R; VAN ZIJL, P.Mutation research. 1988, Vol 204, Num 4, pp 655-663, issn 0027-5107Article

The mechanism of inhibition of DNA replication in HeLa S3 cells by the antitumor drug Ledakrin and other antitumor 1-nitro-9-aminoacridinesWOYNAROWSKI, J. M; BARTOSZEK, A.Biochimica et biophysica acta. 1985, Vol 825, Num 2, pp 244-253, issn 0006-3002Article

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